Baker's Yeast

Yeast have been a powerful model to study a host of biological phenomena.  Their powerful genetic approaches are now being tapped into to study neuronal proteins that interface with basic cellular machinery.  In particular, yeast models of protein folding diseases have been developed to investigate mechanisms of cytotoxicity and to screen for nov el therapeutic targets for a host of neurological disorders, including Parkinson’s Disease, Huntington’s D isease, Prion Diseases and Alzheimer’s Disease.  For more information on how this model system is being employed to study protein folding disorders of the brain, visit the lab of Susan Lindquist.